Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853059 | 0.93 | CSF1R (0.34) | CSF1RPDGFRBNAMPTSCN9AKDR | |
| SCHEMBL29593254 | 0.86 | AKR1C3 (0.37) | CSF1RPDGFRBNAMPTAKR1C3SCN9A | |
| SCHEMBL23218815 | 0.86 | AKR1C3 (0.37) | CSF1RPDGFRBNAMPTAKR1C3SCN9A | |
| SCHEMBL28736114 | 0.80 | AKR1C3 (0.33) | CSF1RPDGFRBAKR1C3SCN9AAKR1C2 | |
| SCHEMBL23218951 | 0.79 | CFD (0.43) | AKR1C3SCN9AAKR1C2MAPTCFD | |
| SCHEMBL29591865 | 0.79 | CFD (0.43) | AKR1C3SCN9AAKR1C2MAPTCFD | |
| SCHEMBL23218950 | 0.78 | DPP4 (0.39) | CSF1RPDGFRBNAMPTSCN9AKDR | |
| SCHEMBL29852921 | 0.78 | DPP4 (0.39) | CSF1RPDGFRBNAMPTSCN9AKDR | |
| SCHEMBL23219218 | 0.78 | POLB (0.36) | MAPTLMNAMEN1USP2ALDH1A1 | |
| SCHEMBL21545236 | 0.77 | CFD (0.42) | PDE10AMAPTCFDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |