Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736106 | 0.90 | CMKLR1 (0.47) | CFDCMKLR1PTGER1CYP1A2KDM4E | |
| SCHEMBL23219154 | 0.88 | CFD (0.40) | CFDPTGER1CYP1A2TBXAS1ELANE | |
| SCHEMBL29852929 | 0.86 | CFD (0.46) | CFDPTGER1CYP1A2TBXAS1ELANE | |
| SCHEMBL23219066 | 0.86 | CFD (0.46) | CFDPTGER1CYP1A2TBXAS1ELANE | |
| SCHEMBL29591752 | 0.86 | CFD (0.46) | CFDPTGER1CYP1A2TBXAS1ELANE | |
| SCHEMBL31018839 | 0.79 | CFD (0.44) | CFDPTGER1CYP1A2TBXAS1ELANE | |
| SCHEMBL29340543 | 0.79 | CFD (0.44) | CFDPTGER1CYP1A2TBXAS1ELANE | |
| SCHEMBL29340529 | 0.79 | CFD (0.44) | CFDPTGER1CYP1A2TBXAS1ELANE | |
| SCHEMBL31018835 | 0.79 | CFD (0.44) | CFDPTGER1CYP1A2TBXAS1ELANE | |
| SCHEMBL23218845 | 0.79 | TBXAS1 (0.42) | CFDPTGER1CYP1A2TBXAS1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |