SCHEMBL23219161 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CFD	P00746	13/20	0.56

▸	F11	P03951	5/20	0.51

▸	TPSB2	P20231	4/20	0.51

▸	PLAU	P00749	2/20	0.51

▸	KLKB1	P03952	2/20	0.51

▸	PLG	P00747	1/20	0.51

▸	F7	P08709	1/20	0.51

▸	MET	P08581	1/20	0.41

▸	SLC2A2	P11168	1/20	0.40

▸	TBXAS1	P24557	1/20	0.39

▸	TGFBR1	P36897	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29852662	1.00	CFD (0.56)	CFDF11TPSB2PLAUKLKB1
SCHEMBL23218541	0.89	CFD (0.66)	CFDF11TPSB2PLAUKLKB1
SCHEMBL29852892	0.89	CFD (0.66)	CFDF11TPSB2PLAUKLKB1
SCHEMBL29852984	0.86	CFD (0.56)	CFDF11TPSB2PLAUKLKB1
SCHEMBL23218082	0.86	CFD (0.56)	CFDF11TPSB2PLAUKLKB1
SCHEMBL28736136	0.82	CFD (0.73)	CFDF11TPSB2PLAUKLKB1
SCHEMBL29592574	0.82	CFD (0.73)	CFDF11TPSB2PLAUKLKB1
SCHEMBL23219125	0.80	TBXAS1 (0.45)	CFDMETSLC2A2TBXAS1
SCHEMBL29852848	0.80	TBXAS1 (0.45)	CFDMETSLC2A2TBXAS1
SCHEMBL23218214	0.78	CFD (0.59)	CFDF11TPSB2PLAUKLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021072198-A1	ORAL COMPLEMENT FACTOR D INHIBITORS	BIOCRYST PHARMACEUTICALS, INC. (US)	2021-04-15	—	—	WO	disclosed
WO-2021072198-A1	ORAL COMPLEMENT FACTOR D INHIBITORS	BIOCRYST PHARMACEUTICALS, INC. (US)	2021-04-15	—	—	WO	disclosed