Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 18/20 | 0.46 |
| ▸ | F11 | P03951 | 2/20 | 0.42 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852833 | 1.00 | CFD (0.46) | CFDF11TPSB2PLAUPLG | |
| SCHEMBL29853068 | 0.90 | CFD (0.55) | CFDF11TPSB2PLAUPLG | |
| SCHEMBL23219053 | 0.90 | CFD (0.55) | CFDF11TPSB2PLAUPLG | |
| SCHEMBL29853043 | 0.85 | MTNR1A (0.34) | CFDMTNR1AMTNR1B | |
| SCHEMBL23219189 | 0.85 | MTNR1A (0.34) | CFDMTNR1AMTNR1B | |
| SCHEMBL23218462 | 0.83 | CFD (0.47) | CFDF11TPSB2PLAUPLG | |
| SCHEMBL29852707 | 0.83 | CFD (0.47) | CFDF11TPSB2PLAUPLG | |
| SCHEMBL23241814 | 0.82 | CFD (0.44) | CFDF11TPSB2PLAUPLG | |
| SCHEMBL28772704 | 0.77 | CFD (0.46) | CFDF11TPSB2PLAUPLG | |
| SCHEMBL30009702 | 0.77 | CFD (0.46) | CFDF11TPSB2PLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |