SCHEMBL23219385

SCHEMBL23219385

COc1ccc(N(c2ccc(OC)cc2)c2ccc(-c3ccc(N(c4ccc(Br)cc4)c4ccc(Br)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
RAB9A P51151 3/20 0.48
MAPT P10636 3/20 0.48
MAPK1 P28482 2/20 0.48
RXFP1 Q9HBX9 2/20 0.48
LMNA P02545 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ESR2 Q92731 1/20 0.47
APP P05067 2/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
MCL1 Q07820 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL680810 1.00 MEN1 (0.48) MEN1KMT2ARAB9AMAPTMAPK1
SCHEMBL15703026 1.00 MEN1 (0.48) MEN1KMT2ARAB9AMAPTMAPK1
SCHEMBL3364659 1.00 MEN1 (0.48) MEN1KMT2ARAB9AMAPTMAPK1
SCHEMBL27064699 0.94 ABL1 (0.49) MEN1KMT2ARAB9AMAPTMAPK1
SCHEMBL578301 0.94 RAB9A (0.53) MEN1KMT2ARAB9AMAPTMAPK1
SCHEMBL8319450 0.94 RAB9A (0.53) MEN1KMT2ARAB9AMAPTMAPK1
SCHEMBL8097578 0.94 RAB9A (0.53) MEN1KMT2ARAB9AMAPTMAPK1
SCHEMBL14621049 0.93 ACHE (0.52) MEN1KMT2ARAB9AMAPTMAPK1
SCHEMBL19660778 0.91 RAB9A (0.46) MEN1KMT2ARAB9AMAPTMAPK1
SCHEMBL14607760 0.91 ESR2 (0.63) MEN1KMT2ARAB9AMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978255-B2 Bichromic bipodal triphenylamine-based dyes with high photo-electron conversion at low light intensities KOIVISTO BRYAN (CA) 2021-04-13 US disclosed