SCHEMBL8097578

SCHEMBL8097578

COc1ccc(N(c2ccc(Br)cc2)c2ccc(N(c3ccc(Br)cc3)c3ccc(OC)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.53
MEN1 O00255 2/20 0.53
MAPT P10636 2/20 0.53
KMT2A Q03164 2/20 0.53
LMNA P02545 2/20 0.53
MAPK1 P28482 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA12 O43570 1/20 0.50
CA14 Q9ULX7 1/20 0.50
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
NPC1 O15118 2/20 0.47
GAA P10253 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PTGES O14684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8319450 1.00 RAB9A (0.53) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL578301 1.00 RAB9A (0.53) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL15703026 0.94 MEN1 (0.48) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL680810 0.94 MEN1 (0.48) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL3364659 0.94 MEN1 (0.48) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL23219385 0.94 MEN1 (0.48) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL12440941 0.92 ACHE (0.58) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL1680170 0.92 CA4 (0.48) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL13429834 0.90 RAB9A (0.46) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL13138736 0.90 MEN1 (0.46) RAB9AMEN1MAPTKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0918811-B1 POLY(ARYLAMINES) AND FILMS THEREOF DOW CHEMICAL CO (US) 2000-12-27 EP disclosed
US-5948552-A Heat-resistant organic electroluminescent device HEWLETT-PACKARD COMPANY (US) 1999-09-07 US disclosed
US-5929194-A POLY(TERT-DI OR POLYARYLAMINE) CONTAINING END GROUPS, IN EACH OCCURANCE SELECTED BY HYDROXY, GLYCIDYL ETHER, ACRYLATE OR METHACRYLATES, ETHENYL, ETHYNYL, VINYLBENZOXY, IMIDES, TRIFLUROVINYL ETHER AND BOUNDED CYCLOBUTENE THE DOW CHEMICAL COMPANY (US) 1999-07-27 US disclosed
EP-0918811-A1 POLY(ARYLAMINES) AND FILMS THEREOF THE DOW CHEMICAL COMPANY (US) 1999-06-02 EP disclosed
US-5728801-A FILMS USEFUL AS CHARGE TRANSPORT LAYERS IN LIGHT-EMITTING DIODES THE DOW CHEMICAL COMPANY (US) 1998-03-17 US disclosed
EP-0827366-A2 Heat-resistant organic electroluminescent device Hewlett-Packard Company (US) 1998-03-04 EP disclosed
WO-1998006773-A1 POLY(ARYLAMINES) AND FILMS THEREOF THE DOW CHEMICAL COMPANY (US) 1998-02-19 WO disclosed