SCHEMBL7006739

SCHEMBL7006739

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(-c4ccc(/C=C(\C#N)C(=O)O)cc4)s3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.65
APP P05067 1/20 0.54
CISD1 Q9NZ45 1/20 0.48
KDM4E B2RXH2 1/20 0.48
SLC16A3 O15427 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
SLC16A1 P53985 1/20 0.48
GPR35 Q9HC97 1/20 0.48
EGFR P00533 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7007659 0.90 MAPT (0.78) MAPTAPPCISD1KDM4ESLC16A3
SCHEMBL12294129 0.90 MAPT (0.78) MAPTAPPCISD1KDM4ESLC16A3
SCHEMBL7006727 0.90 CISD1 (0.55) CISD1KDM4ESLC16A3ALDH1A1CYP3A4
SCHEMBL10046555 0.90 CISD1 (0.55) CISD1KDM4ESLC16A3ALDH1A1CYP3A4
SCHEMBL12294131 0.89 MAPT (0.80) MAPTAPPCISD1KDM4ESLC16A3
SCHEMBL10058492 0.89 CISD1 (0.59) CISD1KDM4ESLC16A3ALDH1A1CYP3A4
SCHEMBL12661978 0.89 CISD1 (0.59) CISD1KDM4ESLC16A3ALDH1A1CYP3A4
SCHEMBL10058489 0.89 CISD1 (0.59) CISD1KDM4ESLC16A3ALDH1A1CYP3A4
SCHEMBL10046554 0.89 CISD1 (0.59) CISD1KDM4ESLC16A3ALDH1A1CYP3A4
SCHEMBL11941572 0.89 CISD1 (0.59) CISD1KDM4ESLC16A3ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL CRY1, DSG1, CRY2 MAPT 4399/4885APP 2553/4885CISD1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.