Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.30 |
| ▸ | CHRNG | P07510 | 1/20 | 0.30 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219438 | 0.85 | RIPK1 (0.36) | RIPK1PDE2AKCNN4CHRM3HDAC3 | |
| SCHEMBL18823456 | 0.85 | ESR1 (0.36) | PDE2AHDAC1HDAC6ESR1AR | |
| SCHEMBL13496391 | 0.79 | NPC1 (0.46) | RIPK1PDE2AKCNN4CHRM3HDAC3 | |
| SCHEMBL14388881 | 0.74 | RIPK1 (0.42) | RIPK1KCNN4CHRM3HDAC3HDAC1 | |
| SCHEMBL828570 | 0.73 | ALDH1A1 (0.46) | KCNN4CHRM3HDAC3HDAC1HDAC2 | |
| SCHEMBL3950869 | 0.73 | ESR1 (0.44) | PDE2AKCNN4CHRM3HDAC3HDAC1 | |
| SCHEMBL17087626 | 0.73 | CYP3A4 (0.39) | ESR1ARESR2CHRNA1CHRNG | |
| SCHEMBL20866516 | 0.73 | RIPK1 (0.39) | RIPK1PDE2AKCNN4CHRM3HDAC3 | |
| SCHEMBL18465139 | 0.72 | IDO1 (0.32) | RIPK1 | |
| SCHEMBL16374831 | 0.72 | TSHR (0.48) | HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975198-B2 | Terpolymerization of carbon monoxide, an olefin, and an epoxide | THE UNIVERSITY OF AKRON (US) | 2021-04-13 | — | — | US | disclosed |