Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 7/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25005888 | 0.86 | ESR1 (0.40) | ESR1ESR2ARPDE2AHDAC1 | |
| SCHEMBL23219437 | 0.85 | RIPK1 (0.37) | RIPK1ESR1ESR2ARKCNN4 | |
| SCHEMBL21099151 | 0.81 | ESR1 (0.41) | RIPK1ESR1ESR2ARKCNN4 | |
| SCHEMBL18522890 | 0.81 | CNR2 (0.40) | RIPK1ESR1ESR2ARKCNN4 | |
| SCHEMBL20866516 | 0.78 | RIPK1 (0.39) | RIPK1ESR1ESR2ARKCNN4 | |
| SCHEMBL23616059 | 0.73 | KCNN4 (0.40) | KCNN4PDE2ACHRM3HDAC3HDAC1 | |
| SCHEMBL13496391 | 0.72 | NPC1 (0.46) | RIPK1KCNN4PDE2ACHRM3HDAC3 | |
| SCHEMBL21474515 | 0.71 | CNR2 (0.54) | — | |
| SCHEMBL3950869 | 0.71 | ESR1 (0.44) | ESR1ESR2ARKCNN4PDE2A | |
| SCHEMBL828570 | 0.71 | ALDH1A1 (0.46) | KCNN4CHRM3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975198-B2 | Terpolymerization of carbon monoxide, an olefin, and an epoxide | THE UNIVERSITY OF AKRON (US) | 2021-04-13 | — | — | US | disclosed |