⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515498 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL18381917 | 0.73 | — | — | |
| SCHEMBL5544928 | 0.69 | — | — | |
| SCHEMBL17080260 | 0.69 | LMNA (0.38) | — | |
| SCHEMBL2566008 | 0.68 | — | — | |
| SCHEMBL17635681 | 0.67 | — | — | |
| SCHEMBL5537391 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL5373758 | 0.65 | — | — | |
| SCHEMBL28212009 | 0.65 | NAMPT (0.38) | — | |
| SCHEMBL9113574 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975088-B2 | Imidazo[2,1-f][1,2,4]triazine compounds as pi3k-y inhibitors | INCYTE CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |