Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918828 | 0.82 | SLC6A2 (0.45) | RENSSTR4 | |
| SCHEMBL30149615 | 0.82 | SLC6A2 (0.45) | RENSSTR4 | |
| Hydrochloric Acid SCHEMBL15010249 | 0.81 | SLC6A2 (0.46) | RENSSTR4 | |
| SCHEMBL5170092 | 0.80 | REN (0.44) | RENSSTR4 | |
| SCHEMBL16471469 | 0.77 | REN (0.46) | RENSSTR4 | |
| SCHEMBL16471470 | 0.77 | REN (0.46) | RENSSTR4 | |
| SCHEMBL3308098 | 0.76 | — | — | |
| SCHEMBL2910492 | 0.75 | SSTR4 (0.48) | RENSSTR4 | |
| SCHEMBL5220792 | 0.75 | SSTR4 (0.48) | RENSSTR4 | |
| SCHEMBL22873631 | 0.75 | SSTR4 (0.48) | RENSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975081-B2 | Substituted fused pyrazole compounds and their use as LRRK2 inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975081-B2 | Substituted fused pyrazole compounds and their use as LRRK2 inhibitors | LRRK2, PARK7, PINK1 | REN 3029/4885SSTR4 4810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.