Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 3/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 5/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321207 | 0.86 | USP30 (0.52) | USP30DEGS1ABL1FEN1ALOX5AP | |
| SCHEMBL2318660 | 0.85 | NPY5R (0.52) | USP30DEGS1TDO2ABL1 | |
| SCHEMBL2318170 | 0.82 | ALDH1A1 (0.55) | USP30DEGS1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL2315755 | 0.75 | USP30 (0.52) | USP30DEGS1ABL1GRIN2B | |
| SCHEMBL2318241 | 0.74 | NPY5R (0.48) | USP30DEGS1SMN1; SMN2ABL1 | |
| SCHEMBL2319143 | 0.73 | NPY5R (0.47) | USP30DEGS1ABL1FEN1ALOX5AP | |
| SCHEMBL14332386 | 0.72 | NPY5R (0.61) | USP30TDO2ABL1 | |
| SCHEMBL2419345 | 0.72 | ABL1 (0.50) | USP30DEGS1ABL1 | |
| SCHEMBL2318895 | 0.72 | RORC (0.47) | USP30TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2318008 | 0.71 | RAB9A (0.51) | USP30DEGS1TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102272120-A | Biologically active amides | — | 2011-12-07 | — | — | CN | disclosed |
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| EP-2352730-A2 | BIOLOGICALLY ACTIVE AMIDES | H. Lundbeck A/S (DK) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | NPY5R, NPY1R, NPY2R | USP30 3697/4885DEGS1 3961/4885TDO2 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.