Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 5/20 | 0.64 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.60 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CHRND | Q07001 | 6/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.51 |
| ▸ | CHRNG | P07510 | 2/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988507 | 0.87 | CHRNB2 (0.65) | PSMB5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL988137 | 0.85 | CHRNB2 (0.71) | PSMB5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL985563 | 0.84 | CHRNB2 (0.77) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL23221700 | 0.84 | PSMB5 (0.65) | PSMB5CTSLCTSBCTSS | |
| SCHEMBL989841 | 0.82 | PSMB5 (0.64) | PSMB5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL15759462 | 0.82 | PSMB5 (0.64) | PSMB5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL987191 | 0.82 | PSMB5 (0.64) | PSMB5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23716763 | 0.82 | CHRNB2 (0.64) | PSMB5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL988166 | 0.82 | CHRNB2 (0.77) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL15692406 | 0.81 | PSMB5 (0.66) | PSMB5CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805237-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |