Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.64 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.64 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.64 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.64 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.58 |
| ▸ | CHRND | Q07001 | 6/20 | 0.54 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.54 |
| ▸ | CHRNG | P07510 | 2/20 | 0.54 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988507 | 0.87 | CHRNB2 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4PSMB5 | |
| SCHEMBL18515624 | 0.86 | OPRD1 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4PSMB5 | |
| SCHEMBL15840456 | 0.86 | CTSL (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CTSL | |
| SCHEMBL988137 | 0.85 | CHRNB2 (0.71) | CHRNB2CHRNB4CHRNA3CHRNA4PSMB5 | |
| SCHEMBL5177591 | 0.85 | CTSS (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL26605054 | 0.85 | CTSS (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL985563 | 0.84 | CHRNB2 (0.77) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL28220264 | 0.84 | CHRNB2 (0.57) | CHRNB2CHRNB4CHRNA3CHRNA4PSMB5 | |
| SCHEMBL8258217 | 0.84 | PSMB5 (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4PSMB5 | |
| SCHEMBL987675 | 0.84 | PSMB5 (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858347-A2 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | Purdue Research Foundation (US) | 2021-08-04 | — | — | EP | disclosed |