Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363011 | 0.82 | BCL2 (0.46) | MAOB | |
| SCHEMBL10620550 | 0.81 | RARB (0.56) | HSD11B1RARBTSHRHSD17B10RARA | |
| SCHEMBL25956648 | 0.81 | HSD11B1 (0.53) | HSD11B1RARBTSHRHSD17B10RARA | |
| SCHEMBL1532723 | 0.80 | LPL (0.49) | — | |
| SCHEMBL2094335 | 0.79 | HSD11B1 (0.47) | HSD11B1RARBTSHRHSD17B10RARA | |
| SCHEMBL28636691 | 0.79 | MAOB (0.65) | HSD11B1RARBMAOBAKR1C2AKR1C1 | |
| SCHEMBL28632619 | 0.79 | TAAR1 (0.65) | HSD11B1RARBRARARARGCA1 | |
| SCHEMBL1091891 | 0.79 | CYP19A1 (0.53) | HSD11B1RARBTSHRHSD17B10MEN1 | |
| SCHEMBL402463 | 0.79 | HSD11B1 (0.68) | HSD11B1RARBTSHRHSD17B10RARA | |
| SCHEMBL9158283 | 0.79 | HSD11B1 (0.68) | HSD11B1RARBTSHRHSD17B10RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350350-B1 | COMPOUNDS AND SYSTEMS FOR IMPROVING SIGNAL DETECTION | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2021-04-14 | — | — | EP | disclosed |