SCHEMBL402463

SCHEMBL402463

CCCCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.68
RARB P10826 6/20 0.63
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 1/20 0.55
RARA P10276 1/20 0.55
MAPT P10636 1/20 0.55
MTOR P42345 1/20 0.55
KMT2A Q03164 1/20 0.55
HSD17B10 Q99714 2/20 0.53
HPGD P15428 1/20 0.53
TSHR P16473 1/20 0.52
TRPV1 Q8NER1 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
FFAR1 O14842 1/20 0.50
KCNH2 Q12809 1/20 0.50
PSMB5 P28074 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9158283 1.00 HSD11B1 (0.68) HSD11B1RARBALDH1A1MEN1RARA
Ethyne SCHEMBL28914485 0.96 HSD11B1 (0.64) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL1203500 0.93 HSD11B1 (0.69) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL28842038 0.92 RARB (0.61) HSD11B1RARBALDH1A1MEN1RARA
Boric Acid SCHEMBL29240144 0.92 RARB (0.61) HSD11B1RARBALDH1A1MEN1RARA
Bicarbonate SCHEMBL27623751 0.92 RARB (0.71) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL5599589 0.91 HSD11B1 (0.67) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL1533772 0.91 HSD11B1 (0.67) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL4598933 0.91 HSD11B1 (0.67) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL9158137 0.91 HSD11B1 (0.67) HSD11B1RARBALDH1A1MEN1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684802-A Nuclear grade high-flame-retardant high-temperature-resistant anti-radiation silicone rubber and preparation method and application thereof 上海电缆研究所有限公司 2025-03-25 CN claimed
CN-118146510-A Heat-resistant polyarylether resin, synthesis method and application thereof in coating aspect 浙江鹏孚隆新材料有限公司 2024-06-07 CN claimed
WO-2023088095-A1 7-FLUORO-5-SUBSTITUTED TRYPTAMINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF 宁波大学 2023-05-25 WO claimed
CN-115784965-A 7-fluoro-5-substituted tryptamine compound and preparation method and application thereof 宁波大学 2023-03-14 CN claimed
CN-113296310-A Quantum dot light conversion layer and preparation method thereof 广东普加福光电科技有限公司 2021-08-24 CN claimed
CN-111215129-A ReOxMethod for catalytically cracking carbon-carbon bond of lignin by HZSM-5 中国科学院大连化学物理研究所 2020-06-02 CN claimed
CN-106119302-A A kind of method of micro-organisms biphenyl carboxylic acids 青岛科技大学 2016-11-16 CN claimed
CN-101240001-B 2' -fluoro nucleosides UNIV EMORY 2013-10-16 CN claimed
US-8377948-B2 Antitumor agents and methods of their use THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2013-02-19 US claimed
CN-102336754-A Synthetic method of entecavir and intermediate compound thereof TAIZHOU AOXIANG MEDICAL TECHNOLOGY CO LTD 2012-02-01 CN claimed
US-7829741-B2 Process for producing α, α-difluoroamine NATIONAL UNIVERSITY CORPORATION (JP) 2010-11-09 US claimed
US-20090177012-A1 PROCESS FOR PRODUCING ALPHA, ALPHA-DIFLUOROAMINE NATIONAL UNIVERSITY CORPORATION, HOKKAIDO UNIVERSITY (JP) 2009-07-09 US claimed
US-20090048265-A1 NOVEL ANTITUMOR AGENTS AND METHODS OF THEIR USE THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2009-02-19 US claimed
EP-1813596-A1 PROCESS FOR PRODUCING ALPHA, ALPHA- DIFLUOROAMINE National University Corporation Hokkaido University (JP) 2007-08-01 EP claimed
CN-88103202-A Vinyl cephalosporin compound that replaces and preparation method thereof and as the application of medicine 1988-12-21 CN claimed
JP-56090880-A None JP disclosed
CN-122055371-A Faster automated iterative C-C bond formation 伊利诺伊大学评议会 2026-05-15 CN disclosed
US-4177156-A SPECIALTY OILS FOR TRANSFORMERS RHONE-POULENC INDUSTRIES (FR) 1979-12-04 US disclosed
US-4154697-A Liquid crystalline hexahydroterphenyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1979-05-15 US disclosed
US-4119555-A COOLANTS FOR TRANSFORMERS RHONE-POULENC INDUSTRIES (FR) 1978-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048265-A1 NOVEL ANTITUMOR AGENTS AND METHODS OF THEIR USE ADRB1, ADRA2A, ADRA1A HSD11B1 1528/4885RARB 474/4885ALDH1A1 219/4885
US-20090177012-A1 PROCESS FOR PRODUCING ALPHA, ALPHA-DIFLUOROAMINE FUCA1, FUCA2, DBH HSD11B1 1102/4885RARB 790/4885ALDH1A1 522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.