SCHEMBL232233

SCHEMBL232233

O=C(O)c1cc(I)ccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.61
ALDH1A1 P00352 4/20 0.61
KDM5A P29375 2/20 0.61
KDM3A Q9Y4C1 2/20 0.61
ASPH Q12797 2/20 0.61
KDM8 Q8N371 2/20 0.61
KDM6B O15054 1/20 0.61
TET3 O43151 1/20 0.61
KDM4A O75164 1/20 0.61
BBOX1 O75936 1/20 0.61
MAPT P10636 1/20 0.61
KDM5C P41229 1/20 0.61
KDM4D Q6B0I6 1/20 0.61
TET2 Q6N021 1/20 0.61
ALKBH5 Q6P6C2 1/20 0.61
KDM7A Q6ZMT4 1/20 0.61
TET1 Q8NFU7 1/20 0.61
EGLN2 Q96KS0 1/20 0.61
FTO Q9C0B1 1/20 0.61
EGLN1 Q9GZT9 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30524416 1.00 KDM4E (0.61) KDM4EALDH1A1KDM5AKDM3AASPH
Iodide SCHEMBL3551537 0.98 KDM4E (0.59) KDM4EALDH1A1KDM5AKDM3AASPH
SCHEMBL5700151 0.81 ALDH1A1 (0.50) KDM4EALDH1A1KDM5AKDM3AASPH
SCHEMBL19918058 0.81 ADORA3 (0.45) KDM4EALDH1A1KDM5AKDM3AASPH
SCHEMBL7513922 0.79 KMO (0.71) KDM4EALDH1A1KDM5AKDM3AASPH
SCHEMBL30800092 0.79 KMO (0.71) KDM4EALDH1A1KDM5AKDM3AASPH
SCHEMBL5700578 0.79 KMT2A (0.59) KDM4EALDH1A1KDM5AKDM3AASPH
SCHEMBL14897947 0.78 KDM4D (0.50) KDM4EALDH1A1KDM5AKDM3AASPH
SCHEMBL2490793 0.76 ALDH1A1 (0.50) KDM4EALDH1A1KDM3AKDM6BMAPT
SCHEMBL17596266 0.76 P2RX7 (0.49) KDM4EALDH1A1KDM5AKDM3AASPH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1709 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
US-12478615-B2 Prolyl hydroxylase inhibitors and methods of use AKEBIA THERAPEUTICS, INC. (US) 2025-11-25 US claimed
CN-120040329-A Ring-opening steroid derivative containing oxime ester, preparation method and application thereof 常州工业职业技术学院 2025-05-27 CN claimed
US-20240358691-A1 PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USE WARNER CHILCOTT COMPANY, LLC (PR) 2024-10-31 US claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-114907201-B Green synthesis method for synthesizing 2-menaquinone 嘉兴学院 2024-05-24 CN claimed
CN-114656461-B Quinoline ring-containing 1,2, 4-oxadiazole substituted benzamide compound and synthetic method and application thereof 浙江工业大学 2024-01-30 CN claimed
CN-114920736-B Quinoline ring-containing 1,2, 4-oxadiazole substituted benzamide compound and preparation method and application thereof 浙江工业大学 2024-01-30 CN claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
CN-1163619-C Method and compositions for determining sequence of nucleic acid molecules �Ѹ�������ѧ��˾ 2004-08-25 CN claimed
CN-1515541-A Method for detecting ligand pair combination by using non-fluorescent marker and its composite ռ�˹ 2004-07-28 CN claimed
US-20020015826-A1 Zwitterionic iodonium compounds and methods of application CLEMSON UNIVERSITY 2002-02-07 US claimed
US-RE37303-E1 Imidazole compounds and their therapeutic applications INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2001-07-31 US claimed
CN-1212021-A Method and compositions for determining sequence of nucleic acid molecules RAPIGENE INC (US) 1999-03-24 CN claimed
CN-1212019-A Methods and compositions for detecting ligand pair binding using non-fluorescent labels RAPIGENE INC (US) 1999-03-24 CN claimed
US-5808164-A Process for producing aromatic sulfides PHILLIPE PETROLEUM COMPANY (US) 1998-09-15 US claimed
US-5708171-A HISTAMINE H3-RECEPTOR ANTAGONIST INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1998-01-13 US claimed
US-5618981-A Process for producing aromatic sulfides PHILLIPS PETROLEUM COMPANY (US) 1997-04-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020015826-A1 Zwitterionic iodonium compounds and methods of application DGKI, DSTN, PCNA KDM4E 2180/4885ALDH1A1 3578/4885KDM5A 1094/4885
US-20240358691-A1 PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USE HIF1AN, EGLN3, EGLN2 KDM4E 503/4885ALDH1A1 735/4885KDM5A 442/4885
US-12478615-B2 Prolyl hydroxylase inhibitors and methods of use HIF1AN, EGLN3, HIF1A KDM4E 562/4885ALDH1A1 444/4885KDM5A 494/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 KDM4E 1567/4885ALDH1A1 1723/4885KDM5A 1358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.