SCHEMBL23225640

SCHEMBL23225640

C=CCCCN(C)C(=O)OCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
LMNA P02545 2/20 0.37
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
TSHR P16473 2/20 0.35
MAPT P10636 4/20 0.35
USP2 O75604 2/20 0.33
CYP3A4 P08684 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RECQL P46063 1/20 0.33
ABCC4 O15439 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
EPHX2 P34913 2/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23225639 0.89 CA12 (0.35) ALDH1A1LMNACHRNB2CHRNB4CHRNA3
SCHEMBL24131324 0.83 TSHR (0.46) ALDH1A1LMNACHRNB2CHRNB4CHRNA3
SCHEMBL995722 0.81 LMNA (0.40) ALDH1A1LMNACHRNB2CHRNB4CHRNA3
SCHEMBL5535643 0.79 CA12 (0.36) ALDH1A1LMNACHRNB2CHRNB4CHRNA3
SCHEMBL9357923 0.79 ALDH1A1 (0.41) ALDH1A1LMNACHRNB2CHRNB4CHRNA3
SCHEMBL17493274 0.78 CHRNB2 (0.46) ALDH1A1LMNACHRNB2CHRNB4CHRNA3
SCHEMBL10292049 0.78 ALDH1A1 (0.46) ALDH1A1LMNACHRNB2CHRNB4CHRNA3
SCHEMBL5546237 0.78 CA12 (0.35) ALDH1A1LMNACHRNB2CHRNB4CHRNA3
SCHEMBL20777122 0.77 HDAC6 (0.36) ALDH1A1LMNATSHRMAPTABCC4
SCHEMBL4006880 0.77 EPHX2 (0.42) ALDH1A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021072140-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS BIOHAVEN THERAPEUTICS LTD. (US) 2021-04-15 WO disclosed