Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | RXRB | P28702 | 1/20 | 0.57 |
| ▸ | RXRG | P48443 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13440181 | 0.93 | FFAR4 (0.58) | FFAR4RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL25682702 | 0.89 | TDP1 (0.57) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL69503 | 0.89 | RXRA (0.57) | FFAR4RXRARXRBRXRGTDP1 | |
| SCHEMBL20059720 | 0.89 | LMNA (0.59) | FFAR4RXRARXRBRXRGTDP1 | |
| SCHEMBL27703866 | 0.87 | FFAR4 (0.58) | FFAR4RXRARXRBRXRGTDP1 | |
| SCHEMBL30141105 | 0.87 | KMT2A (0.62) | RXRATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL3960907 | 0.87 | KMT2A (0.62) | RXRATDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL13440174 | 0.87 | RXRA (0.70) | FFAR4RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL24851614 | 0.86 | FFAR4 (0.51) | FFAR4RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL23362754 | 0.86 | FFAR4 (0.51) | FFAR4RXRARXRBRXRGMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637398-B2 | Radiohalogen prosthetic moieties and radiolabeled biomolecules | DUKE UNIVERSITY (US) | 2026-05-26 | — | — | US | disclosed |
| US-20230002293-A1 | RADIOHALOGEN PROSTHETIC MOIETIES AND RADIOLABELED BIOMOLECULES | UNIV DUKE (US) | 2023-01-05 | — | — | US | disclosed |
| US-20230002293-A1 | RADIOHALOGEN PROSTHETIC MOIETIES AND RADIOLABELED BIOMOLECULES | UNIV DUKE (US) | 2023-01-05 | — | — | US | disclosed |
| EP-4058423-A1 | RADIOHALOGEN PROSTHETIC MOIETIES AND RADIOLABELED BIOMOLECULES | Duke University (US) | 2022-09-21 | — | — | EP | disclosed |
| WO-2021096968-A1 | RADIOHALOGEN PROSTHETIC MOIETIES AND RADIOLABELED BIOMOLECULES | DUKE UNIVERSITY (US) | 2021-05-20 | — | — | WO | disclosed |
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002293-A1 | RADIOHALOGEN PROSTHETIC MOIETIES AND RADIOLABELED BIOMOLECULES | CD47, SHBG, KLK3 | FFAR4 3269/4885RXRA 126/4885RXRB 123/4885 |
| US-12637398-B2 | Radiohalogen prosthetic moieties and radiolabeled biomolecules | CD47, KLK3, SHBG | FFAR4 3522/4885RXRA 203/4885RXRB 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.