Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601224 | 0.86 | RXFP1 (0.58) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL11932852 | 0.81 | RXFP1 (0.53) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL2429572 | 0.78 | RXFP1 (0.53) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL1693205 | 0.78 | RXFP1 (0.53) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL31347764 | 0.78 | RXFP1 (0.53) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL5735731 | 0.78 | ALDH1A1 (0.43) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL9224065 | 0.78 | RXFP1 (0.49) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL2624005 | 0.78 | MAPT (0.50) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL10896232 | 0.77 | ALDH1A1 (0.50) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL265392 | 0.77 | ALDH1A1 (0.55) | RXFP1CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097491-A1 | BENZIMIDAZOLE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-08-11 | — | — | WO | disclosed |