Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13285783 | 0.74 | RIPK1 (0.38) | — | |
| SCHEMBL22686232 | 0.68 | RIPK1 (0.35) | — | |
| SCHEMBL22638996 | 0.67 | RIPK1 (0.36) | — | |
| SCHEMBL17975504 | 0.66 | CSNK1E (0.34) | — | |
| SCHEMBL17613248 | 0.65 | RIPK1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL16569842 | 0.64 | ADRB1 (0.37) | — | |
| SCHEMBL2276427 | 0.63 | RIPK1 (0.42) | — | |
| SCHEMBL16446528 | 0.62 | MAPT (0.51) | — | |
| SCHEMBL21050393 | 0.61 | PSEN1 (0.38) | — | |
| SCHEMBL18971164 | 0.61 | PSEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021070090-A1 | 2-AZASPIRO[3.4]OCTANE DERIVATIVES AS M4 AGONISTS | NOVARTIS AG (CH) | 2021-04-15 | — | — | WO | disclosed |