Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2323211 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KMT2AHPGDCTSDRAB9A | |
| SCHEMBL2323583 | 0.90 | KMT2A (0.52) | ALDH1A1KMT2AHPGDCTSDRAB9A | |
| SCHEMBL2323581 | 0.90 | KMT2A (0.52) | ALDH1A1KMT2AHPGDCTSDRAB9A | |
| SCHEMBL2332534 | 0.90 | KMT2A (0.60) | ALDH1A1KMT2AHPGDCTSDRAB9A | |
| SCHEMBL2332541 | 0.90 | KMT2A (0.60) | ALDH1A1KMT2AHPGDCTSDRAB9A | |
| SCHEMBL2330660 | 0.89 | CTSD (0.55) | ALDH1A1KMT2AHPGDCTSDRAB9A | |
| SCHEMBL2330662 | 0.89 | CTSD (0.55) | ALDH1A1KMT2AHPGDCTSDRAB9A | |
| SCHEMBL2329628 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KMT2AHPGDCTSDRAB9A | |
| SCHEMBL2330575 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AHPGDCTSDRAB9A | |
| SCHEMBL2328058 | 0.80 | KMT2A (0.62) | ALDH1A1KMT2AHPGDCTSDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356979-B1 | ANTI-WRINKLE AGENTS | POLA CHEM IND INC (JP) | 2017-10-25 | — | — | EP | disclosed |
| EP-3173063-A1 | ANTI-WRINKLE AGENTS | Pola Chemical Industries Inc. (JP) | 2017-05-31 | — | — | EP | disclosed |
| CN-102215812-B | Anti-wrinkle agents | POLA CHEM IND INC | 2014-09-10 | — | — | CN | disclosed |
| EP-2356979-A1 | ANTI-WRINKLE AGENTS | Pola Chemical Industries Inc. (JP) | 2011-08-17 | — | — | EP | disclosed |