SCHEMBL2330660

SCHEMBL2330660

COC(=O)C(CSC)NC(=O)c1ccccc1OC

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.55
HPGD P15428 3/20 0.55
KMT2A Q03164 2/20 0.55
ALDH1A1 P00352 1/20 0.55
RAB9A P51151 2/20 0.53
TSHR P16473 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
TP53 P04637 1/20 0.49
GLA P06280 1/20 0.49
LMNA P02545 1/20 0.49
STAT3 P40763 1/20 0.49
NPC1 O15118 1/20 0.48
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2330662 1.00 CTSD (0.55) CTSDHPGDKMT2AALDH1A1RAB9A
SCHEMBL2323581 0.91 KMT2A (0.52) CTSDHPGDKMT2AALDH1A1RAB9A
SCHEMBL2323583 0.91 KMT2A (0.52) CTSDHPGDKMT2AALDH1A1RAB9A
SCHEMBL2323210 0.89 ALDH1A1 (0.53) CTSDHPGDKMT2AALDH1A1RAB9A
SCHEMBL2323211 0.89 ALDH1A1 (0.53) CTSDHPGDKMT2AALDH1A1RAB9A
SCHEMBL2326548 0.88 KMT2A (0.66) CTSDHPGDKMT2AALDH1A1RAB9A
SCHEMBL2326551 0.88 KMT2A (0.66) CTSDHPGDKMT2AALDH1A1RAB9A
SCHEMBL12984496 0.86 CTSD (0.58) CTSDHPGDKMT2AALDH1A1RAB9A
SCHEMBL12984142 0.84 CTSD (0.56) CTSDHPGDKMT2AALDH1A1RAB9A
SCHEMBL2327455 0.84 CTSD (0.56) CTSDHPGDKMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356979-B1 ANTI-WRINKLE AGENTS POLA CHEM IND INC (JP) 2017-10-25 EP disclosed
EP-3173063-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2017-05-31 EP disclosed
CN-102215812-B Anti-wrinkle agents POLA CHEM IND INC 2014-09-10 CN disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed