Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324572 | 0.91 | FPR2 (0.68) | FPR2KDM4EHCRTR2 | |
| SCHEMBL2327821 | 0.90 | FPR2 (0.55) | FPR2KDM4EHCRTR2 | |
| SCHEMBL2331127 | 0.85 | FPR2 (0.64) | FPR2HCRTR2MEN1KMT2A | |
| SCHEMBL2330742 | 0.84 | FPR2 (0.64) | FPR2KDM4ESMN1; SMN2HCRTR2NPC1 | |
| SCHEMBL2331053 | 0.83 | FPR2 (0.54) | FPR2HCRTR2 | |
| SCHEMBL2324311 | 0.83 | FPR2 (0.65) | FPR2HCRTR2MEN1KMT2A | |
| SCHEMBL2327628 | 0.83 | FPR2 (0.57) | FPR2HCRTR2MEN1KMT2A | |
| SCHEMBL2324771 | 0.82 | FPR2 (0.62) | FPR2KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2324139 | 0.82 | FPR2 (0.64) | FPR2KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1703917 | 0.80 | FPR2 (0.66) | FPR2KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | claimed |
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | disclosed |