Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 8/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327628 | 0.91 | FPR2 (0.57) | FPR2MEN1KMT2AHCRTR2HCRTR1 | |
| SCHEMBL2331127 | 0.89 | FPR2 (0.64) | FPR2MEN1KMT2AHCRTR2HCRTR1 | |
| SCHEMBL2327821 | 0.89 | FPR2 (0.55) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2330742 | 0.89 | FPR2 (0.64) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2324572 | 0.88 | FPR2 (0.68) | FPR2GSK3BHCRTR2HCRTR1 | |
| SCHEMBL2331053 | 0.87 | FPR2 (0.54) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2327045 | 0.84 | FPR2 (0.65) | FPR2MEN1KMT2AGSK3BHCRTR2 | |
| SCHEMBL2324747 | 0.83 | FPR2 (0.67) | FPR2MEN1KMT2AGSK3BHCRTR2 | |
| SCHEMBL2323375 | 0.83 | FPR2 (0.62) | FPR2MEN1KMT2AHCRTR2 | |
| SCHEMBL1703664 | 0.81 | FPR2 (0.68) | FPR2MEN1KMT2AGSK3BHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | claimed |
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | disclosed |