Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 11/20 | 0.57 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324311 | 0.91 | FPR2 (0.65) | FPR2HCRTR2HCRTR1MEN1KMT2A | |
| SCHEMBL2327821 | 0.88 | FPR2 (0.55) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2330327 | 0.88 | FPR2 (0.68) | FPR2 | |
| SCHEMBL2331127 | 0.87 | FPR2 (0.64) | FPR2HCRTR2HCRTR1MEN1KMT2A | |
| SCHEMBL2330742 | 0.86 | FPR2 (0.64) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2324572 | 0.86 | FPR2 (0.68) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2331053 | 0.85 | FPR2 (0.54) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2327503 | 0.85 | FPR2 (0.57) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2326935 | 0.84 | FPR2 (0.58) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2323375 | 0.83 | FPR2 (0.62) | FPR2HCRTR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | claimed |
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | disclosed |