SCHEMBL23236822

SCHEMBL23236822

CNC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NO)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BMP1 P13497 3/20 0.36
▸ FURIN P09958 5/20 0.36
▸ MMP9 P14780 5/20 0.34
▸ MMP1 P03956 2/20 0.34
▸ MMP3 P08254 2/20 0.34
▸ C3AR1 Q16581 1/20 0.34
▸ SIRT5 Q9NXA8 1/20 0.33
▸ SIRT6 Q8N6T7 1/20 0.33
▸ SIRT1 Q96EB6 1/20 0.33
▸ MMP2 P08253 3/20 0.33
▸ MMP8 P22894 2/20 0.33
▸ ADAM10 O14672 1/20 0.32
▸ MMP12 P39900 1/20 0.32
▸ MMP14 P50281 1/20 0.32
▸ ADAM8 P78325 1/20 0.32
▸ ADAM17 P78536 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23736705 0.90 FURIN (0.36) BMP1FURINMMP9MMP1MMP3
SCHEMBL20159819 0.90 FURIN (0.36) BMP1FURINMMP9MMP1MMP3
SCHEMBL20795891 0.90 FURIN (0.36) BMP1FURINMMP9MMP1MMP3
SCHEMBL25832984 0.88 FURIN (0.35) BMP1FURINMMP9MMP1MMP3
SCHEMBL22351933 0.88 FURIN (0.37) BMP1FURINMMP9MMP1MMP3
SCHEMBL19996650 0.88 FURIN (0.37) BMP1FURINMMP9MMP1MMP3
SCHEMBL21897483 0.88 FURIN (0.39) BMP1FURINMMP9MMP1MMP3
SCHEMBL17758699 0.88 FURIN (0.37) BMP1FURINMMP9MMP1MMP3
SCHEMBL22698746 0.86 FURIN (0.38) BMP1FURINC3AR1SIRT5SIRT6
SCHEMBL23961922 0.86 FURIN (0.34) BMP1FURINMMP9MMP1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210108207-A1 OLIGONUCLEOTIDE DERIVATIVE OR SALT THEREOF KYOWA KIRIN CO., LTD. (JP) 2021-04-15 — — US disclosed
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