Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361037 | 0.85 | HTT (0.54) | HTTALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL10572472 | 0.82 | KMT2A (0.50) | HTTALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL27692058 | 0.80 | PKM (0.41) | ALDH1A1PKMNPSR1LMNATOP2A | |
| SCHEMBL18672228 | 0.76 | TDP1 (0.40) | PKMMAPTRECQLNPC1CYP1A2 | |
| SCHEMBL10824672 | 0.75 | KMT2A (0.41) | HTTALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL2323909 | 0.75 | GAA (0.41) | HTTALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL29451310 | 0.75 | ALDH1A1 (0.53) | HTTALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL9234092 | 0.74 | HTT (0.57) | HTTALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL9372035 | 0.73 | HTT (0.44) | HTTALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL26906449 | 0.72 | TDP1 (0.40) | ALDH1A1SMN1; SMN2PKMPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85108650-A | The preparation method of pyridazinone derivative, and insecticidal constituent kill acaricidal composition, and the nematicide composition kills (very) bacterium composition | — | 1986-09-24 | — | — | CN | disclosed |