Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21238177 | 0.91 | NPSR1 (0.54) | NPSR1ALDH1A1TSHRGSK3AGSK3B | |
| SCHEMBL11763831 | 0.77 | TSHR (0.47) | NPSR1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL1008759 | 0.73 | ALDH1A1 (0.55) | NPSR1ALDH1A1GSK3AGSK3BKDM4E | |
| SCHEMBL11206104 | 0.73 | ALDH1A1 (0.59) | NPSR1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL23237686 | 0.71 | ALDH1A1 (0.42) | ALDH1A1GSK3AGSK3BHTTCYP3A4 | |
| SCHEMBL12999586 | 0.70 | HTT (0.39) | ALDH1A1GSK3AGSK3BHTTKDM4E | |
| SCHEMBL1006937 | 0.69 | CYP3A4 (0.57) | NPSR1ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL6864609 | 0.69 | CYP3A4 (0.38) | NPSR1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL1008039 | 0.69 | CYP3A4 (0.52) | NPSR1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15946204 | 0.69 | CYP3A4 (0.52) | NPSR1ALDH1A1HTTKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220356297-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL CORPORATION (JP) | 2022-11-10 | — | — | US | disclosed |
| WO-2021070919-A1 | HETEROCYCLIC-COMPOUND-CONTAINING COMPOSITION FOR FORMING RESIST UNDERLAYER FILM | 日産化学株式会社 | 2021-04-15 | — | — | WO | disclosed |