Ribose (Furanose)

Ribose (Furanose)

SCHEMBL2324435

N=C(N)c1ccccc1.OC[C@H]1OC(O)[C@H](O)[C@@H]1O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.52
F10 P00742 1/20 0.52
F12 P00748 1/20 0.52
F7 P08709 1/20 0.52
F3 P13726 1/20 0.52
PKM P14618 1/20 0.52
BLM P54132 1/20 0.50
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
C1S P09871 1/20 0.48
PRSS3 P35030 1/20 0.48
RECQL P46063 1/20 0.48
KMT2A Q03164 1/20 0.48
HK1 P19367 2/20 0.46
HK2 P52789 2/20 0.46
SLC5A2 P31639 3/20 0.42
PNP P00491 2/20 0.42
WDR5 P61964 1/20 0.42
PYGL P06737 2/20 0.41
LGALS9 O00182 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ribose (Furanose) SCHEMBL502653 0.85 HK1 (0.53) BLMRECQLHK1HK2LGALS9
Ribose (Furanose) SCHEMBL28058976 0.80 HK1 (0.47) HK1HK2SLC5A2
Dextrose SCHEMBL19252827 0.79 HK1 (0.53) HK1HK2PYGLLGALS9LGALS1
D-Mannose SCHEMBL28626185 0.78 SLC5A2 (0.49) HK1HK2SLC5A2
D-Galactose SCHEMBL27638902 0.78 SLC5A2 (0.49) HK1HK2SLC5A2
D-Mannose SCHEMBL1660734 0.78 SLC5A2 (0.64) HK1HK2SLC5A2PYGL
Ribose (Furanose) SCHEMBL5139187 0.77 PYGL (0.47) HK1HK2SLC5A2PYGL
Ribose (Furanose) SCHEMBL27934652 0.77 PYGL (0.47) HK1HK2SLC5A2PYGL
B-D-Galactose SCHEMBL27766291 0.76 LGALS1 (0.52) HK1HK2SLC5A2LGALS9LGALS1
B-D-Galactose SCHEMBL28251165 0.76 LGALS1 (0.52) HK1HK2SLC5A2LGALS9LGALS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023225466-A2 INHIBITING PURINE BIOSYNTHESIS TO INCREASE FAVIPIRAVIR POTENCY AGAINST RNA VIRUS INFECTIONS VIRIOM, INC. (US) 2023-11-23 WO claimed
WO-2023225466-A2 INHIBITING PURINE BIOSYNTHESIS TO INCREASE FAVIPIRAVIR POTENCY AGAINST RNA VIRUS INFECTIONS VIRIOM, INC. (US) 2023-11-23 WO disclosed
US-8012948-B2 Fas/FasL or other death receptor targeted methods and compositions for killing tumor cells PROMISING FUTURE, LLC (US) 2011-09-06 US disclosed
EP-2355833-A2 FAS/FASL OR OTHER DEATH RECEPTOR TARGETED METHODS AND COMPOSITIONS FOR KILLING TUMOR CELLS Promising Future, Llc (US) 2011-08-17 EP disclosed
US-20100324116-A1 FAS/FASL OR OTHER DEATH RECEPTOR TARGETED METHODS AND COMPOSITIONS FOR KILLING TUMOR CELLS PROMISING FUTURE, LLC 2010-12-23 US disclosed
WO-2010045369-A2 FAS/FASL OR OTHER DEATH RECEPTOR TARGETED METHODS AND COMPOSITIONS FOR KILLING TUMOR CELLS PROMISING FUTURE, LLC (US) 2010-04-22 WO disclosed
US-20040248830-A1 Agents that regulate apoptosis IMMASOL, INCORPORATED 2004-12-09 US disclosed
EP-1474175-A2 AGENTS THAT REGULATE APOPTOSIS Immusol Incorporated (US) 2004-11-10 EP disclosed
WO-2002092840-A2 AGENTS THAT REGULATE APOPTOSIS IMMUSOL INCORPORATED (US) 2002-11-21 WO disclosed