Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23244710 | 0.87 | ALDH1A1 (0.55) | TERTRELAADAMTS5ALDH1A1HPGD | |
| SCHEMBL23244715 | 0.87 | RELA (0.47) | TERTRELASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1218847 | 0.82 | TLR4 (0.53) | LMNA | |
| SCHEMBL575075 | 0.82 | — | — | |
| SCHEMBL6206121 | 0.82 | RHEB (0.52) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL29924283 | 0.82 | RHEB (0.52) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL5508642 | 0.81 | MAPT (0.54) | TERTADAMTS5ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30758642 | 0.81 | MAPT (0.54) | TERTADAMTS5ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16890555 | 0.80 | RHEB (0.50) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL10715309 | 0.78 | MAPT (0.54) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11629129-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-20210114984-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210114984-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | PRF1, CASP1, MSR1 | TERT 4451/4885RELA 3534/4885SLC6A4 3410/4885 |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, MSR1 | TERT 4451/4885RELA 3534/4885SLC6A4 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.