SCHEMBL2324580

SCHEMBL2324580

COC(=O)C(CCCCN)NC(=O)OC(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 8/20 0.54
ITGA2B P08514 8/20 0.54
CTSK P43235 7/20 0.48
CTSS P25774 3/20 0.46
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC6 Q9UBN7 1/20 0.43
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1904291 1.00 ITGB3 (0.54) ITGB3ITGA2BCTSKCTSSHDAC4
SCHEMBL8823986 1.00 ITGB3 (0.54) ITGB3ITGA2BCTSKCTSSHDAC4
Hydrochloric Acid SCHEMBL28012371 0.98 ITGB3 (0.53) ITGB3ITGA2BCTSKCTSSHDAC4
Hydrochloric Acid SCHEMBL18982338 0.98 ITGB3 (0.53) ITGB3ITGA2BCTSKCTSSHDAC4
Hydrochloric Acid SCHEMBL3056203 0.98 ITGB3 (0.53) ITGB3ITGA2BCTSKCTSSHDAC4
Hydrochloric Acid SCHEMBL27573111 0.98 ITGB3 (0.53) ITGB3ITGA2BCTSKCTSSHDAC4
Acetic Acid SCHEMBL6813701 0.96 ITGB3 (0.54) ITGB3ITGA2BCTSKCTSSHDAC4
SCHEMBL14366085 0.95 ITGB3 (0.50) ITGB3ITGA2BCTSKCTSSHDAC4
SCHEMBL6646260 0.95 ITGB3 (0.50) ITGB3ITGA2BCTSKCTSSHDAC4
SCHEMBL17445159 0.94 ITGB3 (0.51) ITGB3ITGA2BCTSKCTSSHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10292940-B2 Hyaluronic acid-based amphiphilic polymer, preparation method and application thereof BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) 2019-05-21 US claimed
EP-3241852-B1 HYALURONIC ACID-BASED AMPHIPHILIC POLYMER, PREPARATION METHOD AND APPLICATION THEREOF BRIGHTGENE BIO MEDICAL TECH CO LTD (CN) 2018-10-17 EP claimed
US-20180092858-A1 Hyaluronic Acid-Based Amphiphilic Polymer, Preparation Method and Application Thereof BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) 2018-04-05 US claimed
CN-104497171-A Hyaluronic-acid-based amphiphilic polymer as well as preparation method and application thereof UNIV SOOCHOW 2015-04-08 CN claimed
US-20250388615-A9 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS ARDELYX, INC. (US) 2025-12-25 US disclosed
US-20250066410-A1 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS ARDELYX, INC. (US) 2025-02-27 US disclosed
CN-117838875-B Drug delivery system for local delivery of therapeutic agents and uses thereof 上海椿安生物医药科技有限公司 2025-01-24 CN disclosed
US-12084472-B2 Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists ARDELYX, INC. (US) 2024-09-10 US disclosed
CN-117838875-A Drug delivery system for local delivery of therapeutic agents and uses thereof 上海椿安生物医药科技有限公司 2024-04-09 CN disclosed
CN-115867319-B Drug delivery system for local delivery of therapeutic agents and uses thereof 上海椿安生物医药科技有限公司 2024-01-02 CN disclosed
US-20230256106-A1 DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF COVAL BIOPHARMA (SHANGHAI) CO., LTD. (CN) 2023-08-17 US disclosed
US-20230256106-A1 DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF COVAL BIOPHARMA (SHANGHAI) CO., LTD. (CN) 2023-08-17 US disclosed
US-20090081803-A1 POLYVIOLOGEN BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS GLUMETRICS INC. (US) 2009-03-26 US disclosed
US-20090081803-A1 POLYVIOLOGEN BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS GLUMETRICS INC. (US) 2009-03-26 US disclosed
US-20080286291-A1 Betulinol Derivatives as Anti-Hiv Agents SAXENA RESEARCH, LLC 2008-11-20 US disclosed
US-20080286291-A1 Betulinol Derivatives as Anti-Hiv Agents SAXENA RESEARCH, LLC 2008-11-20 US disclosed
EP-0184550-B1 5-AMINO-4-HYDROXY VALERYL AMIDE DERIVATIVES CIBA-GEIGY AG (CH) 1992-03-18 EP disclosed
EP-0236734-A2 5-Amino-4-hydroxyvaleryl derivatives substituted by s-containing groups CIBA-GEIGY AG (CH) 1987-09-16 EP disclosed
EP-0184550-A2 5-Amino-4-hydroxy valeryl amide derivatives CIBA-GEIGY AG (CH) 1986-06-11 EP disclosed
EP-0010405-B1 STABLE IMMUNOCHEMICAL ASSAY REAGENT FOR THE DETERMINATION OF HAPTENS, AND ASSAY METHOD USING SAID REAGENT TEIKOKU HORMONE MFG. CO., LTD. (JP) 1983-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10292940-B2 Hyaluronic acid-based amphiphilic polymer, preparation method and application thereof CD44, HCAR1, ASGR1 ITGB3 905/4885ITGA2B 546/4885CTSK 2825/4885
US-20180092858-A1 Hyaluronic Acid-Based Amphiphilic Polymer, Preparation Method and Application Thereof CD44, HCAR1, ASGR1 ITGB3 905/4885ITGA2B 546/4885CTSK 2825/4885
US-20230256106-A1 DRUG DELIVERY SYSTEM FOR LOCALLY DELIVERING THERAPEUTIC AGENTS AND USES THEREOF TIE1, TEK, KDR ITGB3 538/4885ITGA2B 374/4885CTSK 1600/4885
US-20250066410-A1 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS GPR119, GIPR, GLP1R ITGB3 3266/4885ITGA2B 4241/4885CTSK 4778/4885
US-20090081803-A1 POLYVIOLOGEN BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS SLC2A4, SLC2A2, SLC2A1 ITGB3 4632/4885ITGA2B 4350/4885CTSK 4503/4885
US-20250388615-A9 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS GPR119, GIPR, FFAR3 ITGB3 3570/4885ITGA2B 4631/4885CTSK 4767/4885
US-12084472-B2 Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists GPR119, GIPR, GLP1R ITGB3 3266/4885ITGA2B 4241/4885CTSK 4778/4885
US-20080286291-A1 Betulinol Derivatives as Anti-Hiv Agents BET1, NFATC1, CD4 ITGB3 1678/4885ITGA2B 3345/4885CTSK 3389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.