SCHEMBL23246136

SCHEMBL23246136

Cn1cc(C(O)C(=O)O)c(=O)[nH]c1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 6/20 0.38
GRIA2 P42262 6/20 0.38
GRIA4 P48058 6/20 0.38
GRIK5 Q16478 6/20 0.38
CYP1A2 P05177 5/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
BLM P54132 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GRIA3 P42263 1/20 0.38
HTT P42858 1/20 0.35
DAO P14920 2/20 0.34
CYP2C9 P11712 2/20 0.34
MAPT P10636 1/20 0.34
CRBN Q96SW2 1/20 0.32
CYP2C19 P33261 3/20 0.31
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TK1 P04183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8672229 0.71 KMT2A (0.45) CYP1A2KMT2AKDM4EHSD17B10HTT
SCHEMBL27810479 0.70 PYGM (0.44) MAPT
SCHEMBL25424962 0.68 KMT2A (0.42) CYP1A2KMT2AKDM4EHSD17B10HTT
SCHEMBL2986044 0.67 DAO (0.46) CYP1A2KMT2AHTTDAOCYP2C9
SCHEMBL40819 0.66 PYGM (0.63)
SCHEMBL103606 0.66 GAA (0.45) CYP1A2KMT2AHTTMAPTGAA
SCHEMBL16248 0.65 MAPK1 (0.47) BLMDAOCRBNTK1
SCHEMBL26669981 0.64 KDM4E (0.64) KMT2AKDM4EHTTMAPTGAA
SCHEMBL643987 0.63 PARP1 (0.39) CYP1A2KMT2AHTTDAOCYP2C9
SCHEMBL23224166 0.63 DAO (0.43) KMT2ABLMHSD17B10DAOCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930823-A Anti-CCR 8 antibodies and uses thereof 乐普创一生物科技(上海)有限公司 2025-05-06 CN disclosed
CN-118742637-A Anti-CCR 8 antibodies and uses thereof 乐普创一生物科技(上海)有限公司 2024-10-01 CN disclosed
CN-117916387-A Compositions and methods for RNA affinity purification 赛诺菲 2024-04-19 CN disclosed
CN-117402871-A Method for purifying messenger RNA 川斯勒佰尔公司 2024-01-16 CN disclosed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN disclosed
CN-116348767-A Method for diagnosing tuberculosis and distinguishing active tuberculosis from latent tuberculosis 西菲伊德公司 2023-06-27 CN disclosed
CN-115515429-A Chewable matrices and their use for collecting saliva samples and for infection detection WM.雷格利 JR.公司 2022-12-23 CN disclosed
WO-2021073626-A1 CHIMERIC ANTIGEN RECEPTOR AND T CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTORS THEREIN 北京门罗生物科技有限公司 2021-04-22 WO disclosed