SCHEMBL16248

SCHEMBL16248

Cc1cn(C)c(=O)[nH]c1=O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.47
HPGD P15428 1/20 0.46
DAO P14920 2/20 0.44
TYMP P19971 1/20 0.44
CRBN Q96SW2 1/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
ALB P02768 1/20 0.40
POLB P06746 1/20 0.40
ADRA1A P35348 1/20 0.40
BLM P54132 1/20 0.40
TK1 P04183 4/20 0.40
TK2 O00142 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6420314 0.98 MAPK1 (0.46) MAPK1HPGDDAOTYMPCRBN
SCHEMBL8952525 0.84 CRBN (0.43) MAPK1HPGDDAOTYMPCRBN
SCHEMBL10105028 0.77 KMT2A (0.40) MAPK1HPGDDAOTYMPALDH1A1
SCHEMBL9910660 0.77 MAPK1 (0.44) MAPK1HPGDTYMPALDH1A1LMNA
SCHEMBL20998663 0.77 CRBN (0.39) MAPK1DAOCRBNALDH1A1
SCHEMBL10105030 0.77 CRBN (0.39) MAPK1DAOCRBNTK1
SCHEMBL19244642 0.76 ALDH1A1 (0.35) MAPK1HPGDTYMPALDH1A1LMNA
SCHEMBL646139 0.76 TDP1 (0.59) MAPK1HPGDTYMPCRBNALDH1A1
SCHEMBL12338478 0.76 DAO (0.40) MAPK1DAOCRBN
SCHEMBL3584096 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1763 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734976-A2 AGENTS FOR TREATING DISORDERS INVOLVING RYANODINE RECEPTORS RyCarma Therapeutics, Inc. (US) 2026-05-06 EP claimed
US-20260048047-A1 SMALL-MOLECULE ACTIVATORS OF MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE SCRIPPS RESEARCH INST (US) 2026-02-19 US claimed
WO-2025006617-A2 AGENTS FOR TREATING DISORDERS INVOLVING RYANODINE RECEPTORS ARMGO PHARMA, INC. (US) 2025-01-02 WO claimed
US-20240177800-A1 ALIGNMENT AND COMPARISON OF GENETIC INFORMATION GEORGE MASON UNIVERSITY 2024-05-30 US claimed
US-20230027396-A1 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS COMERA LIFE SCIENCES, INC. 2023-01-26 US claimed
EP-4065166-A1 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS Comera Life Sciences, Inc. (US) 2022-10-05 EP claimed
WO-2021108427-A1 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS REFORM BIOLOGICS, LLC (US) 2021-06-03 WO claimed
US-10023863-B2 Therapeutics with conformationally restricted monomers MARINA BIOTECH, INC. (US) 2018-07-17 US claimed
EP-3157573-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
US-9579332-B2 Phosphonate analogs of HIV inhibitor compounds GILEAD SCIENCES, INC. (US) 2017-02-28 US claimed
EP-0719267-A4 SECOND MESSENGER CELL SIGNALING INHIBITORS CELL THERAPEUTICS INC (US) 1996-02-16 EP claimed
EP-0623133-A4 SUBSTITUTED AMINO ALKYL COMPOUNDS. CELL THERAPEUTICS INC (US) 1995-10-11 EP claimed
WO-1995022546-A1 INTRACELLULAR SIGNALLING MEDIATORS CELL THERAPEUTICS, INC. (US) 1995-08-24 WO claimed
WO-1994022863-A9 SECOND MESSENGER CELL SIGNALING INHIBITORS 1994-12-22 WO claimed
EP-0623133-A1 SUBSTITUTED AMINO ALKYL COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-11-09 EP claimed
WO-1994024133-A1 RING-SUBSTITUTED CELL SIGNALING INHIBITORS CELL THERAPEUTICS, INC. (US) 1994-10-27 WO claimed
WO-1994022449-A1 THERAPEUTIC COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-10-13 WO claimed
WO-1994022863-A1 SECOND MESSENGER CELL SIGNALING INHIBITORS CELL THERAPEUTICS, INC. (US) 1994-10-13 WO claimed
WO-1994015606-A1 OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-07-21 WO claimed
WO-1994011370-A1 SUBSTITUTED AMINO ALKYL COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-05-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048047-A1 SMALL-MOLECULE ACTIVATORS OF MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE FNTB, PDE7A, TBL3 MAPK1 1861/4885HPGD 2048/4885DAO 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.