Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23263223 | 0.81 | ACACB (0.42) | — | |
| SCHEMBL16269035 | 0.69 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1LMNA | |
| SCHEMBL3633446 | 0.69 | CA12 (0.51) | — | |
| SCHEMBL17654337 | 0.67 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL23706089 | 0.66 | ALDH1A1 (0.50) | ALDH1A1LMNA | |
| SCHEMBL3125858 | 0.66 | DRD2 (0.41) | — | |
| SCHEMBL2535627 | 0.66 | S1PR2 (0.39) | ALDH1A1 | |
| SCHEMBL23263288 | 0.63 | CYP2D6 (0.35) | — | |
| SCHEMBL444439 | 0.63 | ALDH1A1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL2531562 | 0.63 | DRD2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021074279-A1 | SPIRO-FUSED TRICYCLIC MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-22 | — | — | WO | disclosed |