Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15401377 | 0.95 | ALDH1A1 (0.36) | ALDH1A1LMNAFAAHOPRM1OPRD1 | |
| SCHEMBL23089089 | 0.84 | FAAH (0.36) | ALDH1A1FAAHOPRM1CYP2C19 | |
| SCHEMBL23089219 | 0.82 | FAAH (0.37) | ALDH1A1FAAHOPRM1PKLRAVPR1A | |
| SCHEMBL23089175 | 0.81 | CA12 (0.39) | FAAHOPRM1OPRD1OPRL1CA12 | |
| SCHEMBL31691821 | 0.81 | HTR1A (0.38) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL30149275 | 0.80 | CYP11B2 (0.42) | OPRD1OPRK1 | |
| SCHEMBL443155 | 0.80 | CYP11B2 (0.42) | OPRD1OPRK1 | |
| SCHEMBL5337601 | 0.80 | OPRD1 (0.36) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL26118197 | 0.79 | PKLR (0.42) | ALDH1A1LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL3511641 | 0.79 | OPRK1 (0.33) | ALDH1A1FAAHOPRD1OPRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748420-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-10 | — | — | US | disclosed |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-8604040-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2013-12-10 | — | — | US | disclosed |
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | ALDH1A1 1009/4885LMNA 533/4885FAAH 4553/4885 |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | ALDH1A1 1051/4885LMNA 699/4885FAAH 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.