SCHEMBL2324813

SCHEMBL2324813

COC(=O)c1cc(C(=O)OC)cc(S(=O)(=O)Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
CA7 P43166 2/20 0.50
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 5/20 0.48
POLB P06746 3/20 0.48
XDH P47989 2/20 0.48
LMNA P02545 2/20 0.48
GAA P10253 1/20 0.48
NFKB1 P19838 1/20 0.48
GFER P55789 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
FUT7 Q11130 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MAPT P10636 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599408 0.96 CA12 (0.50) CA12CA1CA2CA9CA14
SCHEMBL13790627 0.93 ALDH1A1 (0.45) CA12CA1CA2CA9CA14
SCHEMBL24298202 0.89 CNR2 (0.46) CA12CA1CA2CA9CA14
SCHEMBL3593345 0.89 ALDH1A1 (0.46) CA12CA1CA2CA9CA14
SCHEMBL19900071 0.88 CA12 (0.43) CA12CA1CA2CA9CA14
SCHEMBL22012125 0.88 CA12 (0.43) CA12CA1CA2CA9CA14
SCHEMBL16903501 0.88 NOTUM (0.55) CA12CA1CA2CA9CA14
SCHEMBL3593036 0.85 NOTUM (0.60) CA12CA1CA2CA9CA14
SCHEMBL22021470 0.84 CA12 (0.40) CA12CA1CA2CA9CA14
SCHEMBL27574884 0.82 ALDH1A1 (0.41) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421548-B1 COLORING COMPOSITION, INKJET RECORDING INK, INKJET RECORDING METHOD, AND INKJET PRINTER CARTRIDGE FUJIFILM CORP (JP) 2024-01-24 EP disclosed
EP-3421547-B1 COLORING COMPOSITION, INK JET RECORDING INK, INK JET RECORDING METHOD, AND INK JET PRINTER CARTRIDGE FUJIFILM CORP (JP) 2023-12-20 EP disclosed
EP-3421549-B1 COLORING COMPOSITION, INKJET RECORDING INK, INKJET RECORDING METHOD, AND INKJET PRINTER CARTRIDGE FUJIFILM CORP (JP) 2023-08-16 EP disclosed
US-20230051589-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2023-02-16 US disclosed
CN-108699349-B Coloring composition, ink for inkjet recording, inkjet recording method, and ink cartridge for inkjet printer 富士胶片株式会社 2021-03-12 CN disclosed
CN-108699350-B Coloring composition, ink for inkjet recording, inkjet recording method, and ink cartridge for inkjet printer 富士胶片株式会社 2021-03-12 CN disclosed
CN-108699348-B Coloring composition, ink for inkjet recording, inkjet recording method, and ink cartridge for inkjet printer 富士胶片株式会社 2021-03-12 CN disclosed
US-10745577-B2 Aqueous solution, coloring composition, ink jet recording ink, ink jet recording method, and ink cartridge FUJIFILM CORPORATION (JP) 2020-08-18 US disclosed
US-10711148-B2 Coloring composition, ink jet recording ink, ink jet recording method, and ink jet printer cartridge FUJIFILM CORPORATION (JP) 2020-07-14 US disclosed
US-10711148-B2 Coloring composition, ink jet recording ink, ink jet recording method, and ink jet printer cartridge FUJIFILM CORPORATION (JP) 2020-07-14 US disclosed
US-6468729-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2002-10-22 US disclosed
US-20010031433-A1 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2001-10-18 US disclosed
EP-1132770-A2 Silver halide photographic light-sensitive material Fuji Photo Film Co., Ltd. (JP) 2001-09-12 EP disclosed
WO-1996034851-A1 BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE ABBOTT LABORATORIES (US) 1996-11-07 WO disclosed
US-5312724-A Support with layer containing indoaniline dye which has at least three acidic substituents FUJI PHOTO FILM CO., LTD. (JP) 1994-05-17 US disclosed
EP-0368429-B1 Fluor-substituted benzene derivatives SCHERING AG (DE) 1994-02-09 EP disclosed
US-5130119-A Sulfonamide or hydroxy fluorine substituted benzene for medical diagnosis SCHERING AKTIENGESELLSCHAFT (DE) 1992-07-14 US disclosed
EP-0368429-A2 Fluor-substituted benzene derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1990-05-16 EP disclosed
US-4035346-A ANTISTATIC E. I. DU PONT DE NEMOURS AND CO. (US) 1977-07-12 US disclosed
US-4006123-A Conductive aliphatic polyester or polyetherester having units containing phosphonium sulfonate groups E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230051589-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NLRP1, NLRP3, NOD1 CA12 2844/4885CA1 3732/4885CA2 1210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.