Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | MITF | O75030 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1558732 | 0.94 | L3MBTL1 (0.60) | L3MBTL1LMNAMITFALDH1A1CYP1A2 | |
| SCHEMBL1559275 | 0.91 | L3MBTL1 (0.63) | L3MBTL1LMNAMITFALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3467161 | 0.89 | L3MBTL1 (0.61) | L3MBTL1LMNAMITFALDH1A1CYP1A2 | |
| SCHEMBL18376211 | 0.80 | L3MBTL1 (0.44) | L3MBTL1LMNAMITFALDH1A1CYP1A2 | |
| SCHEMBL20781127 | 0.80 | L3MBTL1 (0.55) | L3MBTL1LMNAMITFALDH1A1CYP1A2 | |
| SCHEMBL8302429 | 0.79 | LMNA (0.61) | L3MBTL1LMNAMITFALDH1A1CYP1A2 | |
| SCHEMBL30079200 | 0.77 | L3MBTL1 (0.59) | L3MBTL1LMNAMITFALDH1A1CYP1A2 | |
| SCHEMBL18131168 | 0.77 | ALDH1A1 (0.50) | L3MBTL1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1557959 | 0.76 | L3MBTL1 (0.67) | L3MBTL1LMNAMITFALDH1A1CYP1A2 | |
| SCHEMBL18048258 | 0.76 | L3MBTL1 (0.42) | L3MBTL1LMNAMITFALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021075476-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 | 2021-04-22 | — | — | WO | disclosed |