Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249700 | 1.00 | LMNA (0.40) | LMNATLR9MAPK1GAAPKM | |
| SCHEMBL2342945 | 0.86 | GAA (0.52) | LMNATLR9MAPK1GAAKMT2A | |
| SCHEMBL5557903 | 0.86 | GAA (0.52) | LMNATLR9MAPK1GAAKMT2A | |
| SCHEMBL24806482 | 0.84 | MAPK1 (0.40) | LMNATLR9MAPK1GAAPKM | |
| SCHEMBL23249579 | 0.83 | POLB (0.40) | LMNATLR9MAPK1GAAKMT2A | |
| SCHEMBL23249580 | 0.83 | POLB (0.40) | LMNATLR9MAPK1GAAKMT2A | |
| SCHEMBL31688093 | 0.81 | LMNA (0.37) | LMNAMAPK1GAAPKMKMT2A | |
| SCHEMBL6686680 | 0.80 | LMNA (0.40) | LMNAMAPK1GAAPKMKMT2A | |
| SCHEMBL10806036 | 0.79 | GAA (0.42) | LMNATLR9GAAPKMKMT2A | |
| SCHEMBL10934289 | 0.79 | TLR9 (0.45) | LMNATLR9MAPK1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12281076-B2 | Process for synthesis of picolinamides | CORTEVA AGRISCIENCE LLC (US) | 2025-04-22 | — | — | US | disclosed |
| US-20220411375-A1 | PROCESS FOR SYNTHESIS OF PICOLINAMIDES | CORTEVA AGRISCIENCE LLC (US) | 2022-12-29 | — | — | US | disclosed |
| EP-4044811-A1 | PROCESS FOR SYNTHESIS OF PICOLINAMIDES | Corteva Agriscience LLC (US) | 2022-08-24 | — | — | EP | disclosed |
| WO-2021076681-A1 | PROCESS FOR SYNTHESIS OF PICOLINAMIDES | DOW AGROSCIENCES LLC (US) | 2021-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411375-A1 | PROCESS FOR SYNTHESIS OF PICOLINAMIDES | NPEPPS, ANPEP, DNPEP | LMNA 989/4885TLR9 4687/4885MAPK1 4349/4885 |
| US-12281076-B2 | Process for synthesis of picolinamides | NPEPPS, ANPEP, DNPEP | LMNA 989/4885TLR9 4687/4885MAPK1 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.