SCHEMBL23251029

SCHEMBL23251029

CO[C@@H]1CCCC[C@H]1OCCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24824549 0.80 — —
SCHEMBL22262713 0.78 — —
SCHEMBL20404232 0.74 KDM4E (0.32) KDM4E
SCHEMBL22262500 0.74 DUT (0.32) —
SCHEMBL22034705 0.72 DUT (0.31) —
SCHEMBL24826714 0.72 RECQL (0.41) —
SCHEMBL11580466 0.71 DUT (0.42) —
SCHEMBL29211291 0.70 — —
SCHEMBL30829443 0.69 DUT (0.31) —
SCHEMBL15043442 0.69 KDM4E (0.37) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10980784-B2 Rapamycin analogs and uses thereof NAVITOR PHARMACEUTICALS, INC. (US) 2021-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10980784-B2 Rapamycin analogs and uses thereof RICTOR, MTOR, RPTOR KDM4E 1565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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