Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320679 | 0.90 | FFAR4 (0.56) | FFAR4MRGPRX4RXRARXRBRXRG | |
| SCHEMBL16178255 | 0.87 | FFAR4 (0.54) | FFAR4MRGPRX4RXRARXRBRXRG | |
| SCHEMBL2318476 | 0.86 | FFAR4 (0.53) | FFAR4MRGPRX4RXRARXRBRXRG | |
| SCHEMBL20059953 | 0.80 | FFAR4 (0.53) | FFAR4MRGPRX4RXRARXRBRXRG | |
| SCHEMBL4507201 | 0.80 | VDR (0.60) | FFAR4MRGPRX4FFAR1VDR | |
| SCHEMBL2950747 | 0.79 | MRGPRX4 (0.55) | FFAR4MRGPRX4RXRARXRBRXRG | |
| SCHEMBL7783922 | 0.77 | FFAR4 (0.60) | FFAR4MRGPRX4RXRARXRBRXRG | |
| SCHEMBL4501862 | 0.77 | HDAC6 (0.57) | FFAR4MRGPRX4VDR | |
| SCHEMBL2972327 | 0.76 | ESR1 (0.59) | FFAR4MRGPRX4VDR | |
| SCHEMBL12295554 | 0.76 | MRGPRX4 (0.68) | FFAR4MRGPRX4RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836177-B1 | VITAMIN D RECEPTOR MODULATORS | LILLY CO ELI (US) | 2011-08-10 | — | — | EP | disclosed |
| US-7659296-B2 | 2-{1-[4-(3,3-dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzooxazole-6-carboxylic acid; 1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzooxazole-6-carboxylic acid amide; stimulate bone formation, restore bone quality, acne, alopecia, Alzheimer's disease etc. | ELI LILLY AND COMPANY (US) | 2010-02-09 | — | — | US | disclosed |
| US-20080119407-A1 | Vitamin D Receptor Modulators | ELI LILLY AND COMPANY | 2008-05-22 | — | — | US | disclosed |
| EP-1836177-A2 | VITAMIN D RECEPTOR MODULATORS | Eli Lilly and Company (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069154-A2 | VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119407-A1 | Vitamin D Receptor Modulators | VDR, CYP2R1, CYP24A1 | FFAR4 94/4885MRGPRX4 89/4885RXRA 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.