Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255286 | 0.96 | KIF11 (0.41) | KIF11PTGDR2TRPV1DGAT1SOAT1 | |
| SCHEMBL23255288 | 0.94 | AKT1 (0.34) | KIF11PTGDR2TRPV1ALOX5APAKT1 | |
| SCHEMBL23255449 | 0.92 | KIF11 (0.34) | KIF11PTGDR2TRPV1ALOX5APCYP3A4 | |
| SCHEMBL21758231 | 0.91 | KIF11 (0.34) | KIF11PTGDR2TRPV1ALOX5APCYP3A4 | |
| SCHEMBL23255299 | 0.90 | TOP1 (0.37) | KIF11TRPV1DGAT1KCNH2TDO2 | |
| SCHEMBL21758723 | 0.90 | ICMT (0.33) | KIF11TRPV1TDO2PTGER4AKT1 | |
| SCHEMBL23255280 | 0.90 | AKT1 (0.34) | KIF11PTGDR2TRPV1DGAT1SOAT1 | |
| SCHEMBL21758517 | 0.89 | TDO2 (0.38) | TDO2PTGER4 | |
| SCHEMBL21758730 | 0.89 | TRPV1 (0.35) | KIF11TRPV1ALOX5APCYP3A4CYP3A5 | |
| SCHEMBL23255450 | 0.88 | CYP3A4 (0.35) | KIF11PTGDR2TRPV1TDO2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |