Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.38 |
| ▸ | TACR1 | P25103 | 4/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255414 | 0.94 | PDE10A (0.38) | PDE10AGPBAR1TACR1KIF11CYP17A1 | |
| SCHEMBL23255690 | 0.93 | GPBAR1 (0.39) | PDE10AGPBAR1TACR1KIF11CYP17A1 | |
| SCHEMBL23255314 | 0.89 | KIF11 (0.38) | PDE10ATACR1KIF11CYP17A1CYP1A2 | |
| SCHEMBL23255442 | 0.88 | KIF11 (0.37) | PDE10AGPBAR1KIF11METAP2 | |
| SCHEMBL23255430 | 0.87 | KIF11 (0.42) | PDE10AKIF11CYP1A2METAP2PDE2A | |
| SCHEMBL18374378 | 0.87 | AR (0.42) | PDE10AKIF11CYP1A2ERBB2NR3C1 | |
| SCHEMBL23255308 | 0.87 | ICMT (0.37) | PDE10AKIF11CYP17A1ERBB2 | |
| SCHEMBL23255435 | 0.87 | GPBAR1 (0.39) | PDE10AGPBAR1TACR1KIF11CYP17A1 | |
| SCHEMBL23255677 | 0.86 | KIF11 (0.40) | PDE10AKIF11CYP17A1CYP1A2METAP2 | |
| SCHEMBL23255605 | 0.86 | PDE10A (0.36) | PDE10AKIF11CYP17A1CYP1A2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |