Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255415 | 0.94 | ICMT (0.36) | ICMTKIF11CYP17A1RPS6KA3ENPP1 | |
| SCHEMBL23255692 | 0.93 | ICMT (0.36) | ICMTKIF11CYP17A1RPS6KA3ENPP1 | |
| SCHEMBL23255314 | 0.92 | KIF11 (0.38) | ICMTKIF11CYP17A1RPS6KA3NPC1 | |
| SCHEMBL23255442 | 0.91 | KIF11 (0.37) | KIF11MEN1NPC1KMT2AATM | |
| SCHEMBL23255677 | 0.90 | KIF11 (0.40) | KIF11CYP17A1GRIN1PDE10AHTR2B | |
| SCHEMBL23255440 | 0.88 | KIF11 (0.39) | KIF11PDE10AHTR2BHTR6MAPT | |
| SCHEMBL23255436 | 0.87 | ICMT (0.36) | ICMTKIF11CYP17A1RPS6KA3ENPP1 | |
| SCHEMBL23255307 | 0.87 | PDE10A (0.39) | KIF11CYP17A1PDE10AERBB2 | |
| SCHEMBL23255430 | 0.86 | KIF11 (0.42) | KIF11PDE10AHTR2BHTR6EPHX2 | |
| SCHEMBL23255416 | 0.86 | PDE10A (0.36) | ICMTKIF11CYP17A1RPS6KA3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |