Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | MAT2A | P31153 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255448 | 0.96 | KIF11 (0.40) | KIF11HTR6HRH1MAT2APDE2A | |
| SCHEMBL23255297 | 0.96 | KIF11 (0.36) | KIF11HTR6HRH1PPARGTRPV1 | |
| SCHEMBL23255493 | 0.91 | MAT2A (0.38) | KIF11HTR6HRH1TRPV1MAT2A | |
| SCHEMBL23255483 | 0.90 | KIF11 (0.39) | KIF11HTR6HRH1TRPV1MAT2A | |
| SCHEMBL23255298 | 0.89 | KIF11 (0.37) | KIF11HTR6HRH1PPARGPPARA | |
| SCHEMBL23255301 | 0.89 | KIF11 (0.37) | KIF11HTR6HRH1PPARGPPARA | |
| SCHEMBL23255299 | 0.87 | TOP1 (0.37) | KIF11TRPV1PDE2APDE10AAKT1 | |
| SCHEMBL23255446 | 0.87 | KIF11 (0.36) | KIF11HTR6HRH1TRPV1PDE2A | |
| SCHEMBL23255491 | 0.86 | TRPV1 (0.38) | KIF11HTR6HRH1TRPV1PDE2A | |
| SCHEMBL21758231 | 0.85 | KIF11 (0.34) | KIF11HTR6HRH1TRPV1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |