Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255299 | 0.93 | TOP1 (0.37) | KIF11AKT1PDE2APDE10ATRPV1 | |
| SCHEMBL23255447 | 0.92 | ICMT (0.36) | KIF11AKT1TRPV1TOP1ICMT | |
| SCHEMBL23255483 | 0.92 | KIF11 (0.39) | KIF11AKT1PDE2APDE10ATRPV1 | |
| SCHEMBL23255300 | 0.90 | TOP1 (0.39) | KIF11AKT1PDE2APDE10ATRPV1 | |
| SCHEMBL23255491 | 0.89 | TRPV1 (0.38) | KIF11AKT1PDE2APDE10ATRPV1 | |
| SCHEMBL23255448 | 0.89 | KIF11 (0.40) | KIF11AKT1PDE2APDE10AHRH1 | |
| SCHEMBL23255603 | 0.88 | TRPV1 (0.35) | KIF11AKT1PDE2APDE10ATRPV1 | |
| SCHEMBL23255285 | 0.88 | KIF11 (0.38) | KIF11AKT1TRPV1TDO2 | |
| SCHEMBL23255485 | 0.88 | PTGDR2 (0.38) | KIF11AKT1PDE2APDE10ATRPV1 | |
| SCHEMBL23255484 | 0.87 | KIF11 (0.40) | KIF11AKT1PDE2APDE10ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |