Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL836840 | 0.94 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL27823718 | 0.92 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL66258 | 0.92 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL27513326 | 0.92 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene Glycol SCHEMBL8740543 | 0.91 | THRB (0.65) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene Glycol SCHEMBL57404 | 0.91 | THRB (0.65) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL28961032 | 0.90 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL28915434 | 0.90 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL16296459 | 0.88 | TSHR (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL867302 | 0.88 | THRB (0.68) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565504-B1 | USE OF A COPOLYMER HAVING AT LEAST ONE GRAFTED ALKOXY OR HYDROXY POLYALKYLENE GLYCOL FUNCTION AS AN AGENT FOR IMPROVING OPTICAL BRIGHTENING ACTIVATION, AND PRODUCTS OBTAINED | COATEX SAS (FR) | 2011-08-10 | — | — | EP | claimed |
| US-20100216962-A1 | METHOD FOR NEUTRALIZING A WATER-SOLUBLE ACRYLIC POLYMER BY AT LEAST ONE MONOVALENT AGENT AND AT LEAST ONE DIVALENT AGENT, AND POLYMERS OBTAINED | COATEX S.A.S (FR) | 2010-08-26 | — | — | US | disclosed |