Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23257628 | 0.89 | EGLN1 (0.34) | CALCRLEGLN1BACE1 | |
| SCHEMBL1393836 | 0.87 | CALCRL (0.36) | CALCRLEGLN1BACE1 | |
| SCHEMBL1274952 | 0.87 | CALCRL (0.36) | CALCRLEGLN1BACE1 | |
| SCHEMBL260667 | 0.87 | CALCRL (0.36) | CALCRLEGLN1BACE1 | |
| SCHEMBL29368427 | 0.87 | CALCRL (0.36) | CALCRLEGLN1BACE1 | |
| SCHEMBL23257603 | 0.85 | LMNA (0.35) | CALCRL | |
| SCHEMBL23257421 | 0.85 | CALCRL (0.32) | CALCRL | |
| SCHEMBL20007592 | 0.83 | EGLN1 (0.38) | CALCRLEGLN1 | |
| SCHEMBL23257909 | 0.82 | POLB (0.34) | CALCRLEGLN1 | |
| SCHEMBL23257332 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210113534-A1 | COMPOUNDS | THE UNIVERSITY OF SHEFFIELD (GB) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113534-A1 | COMPOUNDS | MRGPRX2, MC2R, ADM2 | CALCRL 9/4885EGLN1 4060/4885BACE1 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.