SCHEMBL23258108

SCHEMBL23258108

CC1=Cc2ccccc2C1S(C)(C)C1=C(C)c2ccccc2C1C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 5/20 0.35
▸ DRD4 P21917 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23257925 0.89 DRD2 (0.33) DRD2DRD4
SCHEMBL23257919 0.84 DRD2 (0.33) DRD2DRD4
SCHEMBL23258062 0.84 DRD2 (0.33) DRD2DRD4
SCHEMBL23172820 0.81 DRD2 (0.31) DRD2DRD4
SCHEMBL23257932 0.79 — —
SCHEMBL23172782 0.77 — —
SCHEMBL23258080 0.74 — —
SCHEMBL23172606 0.74 — —
SCHEMBL23258763 0.74 BRD4 (0.31) DRD2DRD4
SCHEMBL23258063 0.72 GPR3 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11427608-B2 Dihydrocarbyl-silyl-bridged-1,3 disubstituted-2-indenyl metallocene complexes for olefin polymerization SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-08-30 — — US disclosed
US-20210115080-A1 DIHYDROCARBYL-SILYL-BRIDGED-1,3 DISUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-04-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210115080-A1 DIHYDROCARBYL-SILYL-BRIDGED-1,3 DISUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION APOL1, ARL1, ZC3HAV1L DRD2 541/4885DRD4 183/4885
US-11427608-B2 Dihydrocarbyl-silyl-bridged-1,3 disubstituted-2-indenyl metallocene complexes for olefin polymerization APOL1, ARL1, ZC3HAV1L DRD2 541/4885DRD4 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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