Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258883 | 0.79 | ELANE (0.40) | ELANEBRD4MTNR1AMTNR1B | |
| SCHEMBL23258507 | 0.78 | AAK1 (0.46) | ELANEMTNR1AMTNR1B | |
| SCHEMBL23258509 | 0.76 | HRH3 (0.41) | ELANEKDM1A | |
| SCHEMBL14839466 | 0.72 | ELANE (0.44) | ELANEBRD4MTNR1AMTNR1B | |
| SCHEMBL23258826 | 0.72 | ELANE (0.41) | ELANEBRD4 | |
| SCHEMBL27839762 | 0.71 | KIF11 (0.35) | KCNN4RORCKDM1A | |
| SCHEMBL23258558 | 0.70 | ELANE (0.40) | ELANEBRD4MTNR1AMTNR1BKDM1A | |
| SCHEMBL23259225 | 0.70 | ELANE (0.40) | ELANEBRD4MTNR1AMTNR1B | |
| SCHEMBL23258536 | 0.70 | PKM (0.43) | ELANEBRD4MTNR1AMTNR1B | |
| SCHEMBL23250692 | 0.70 | OPRD1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |